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human DYM shRNA silencing Adenovirus

Name 
Ad-h-DYM-shRNA
Cat No 
shADV-207456
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human DYM.

shADV-207456
Ad-h-DYM-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DYM (dymeclin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DMC; SMC
Description (Vector)
DYM encodes a protein which is necessary for normal skeletal development and brain function. Mutations in this gene are associated with two types of recessive osteochondrodysplasia, Dyggve-Melchior-Clausen (DMC) dysplasia and Smith-McCort (SMC) dysplasia, which involve both skeletal defects and mental retardation.
Gene ID
54808
Gene Name (Vector)
dymeclin
Gene Symbol
DYM
HGNC ID
HGNC:21317
ORF Size (aa)
2010
ORF Size (bp)
2010 bp
RefSeq ID
NM_017653
RefSeq Synonyms
NM_017653, BC064394,
Species
human
UniGene ID
Hs.162996

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.