human DYM shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DYM.
shAAV-207456
AAV-h-DYM-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DYM (dymeclin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DMC; SMC
Description (Vector)
DYM encodes a protein which is necessary for normal skeletal development and brain function. Mutations in this gene are associated with two types of recessive osteochondrodysplasia, Dyggve-Melchior-Clausen (DMC) dysplasia and Smith-McCort (SMC) dysplasia, which involve both skeletal defects and mental retardation.
Gene ID
54808
Gene Name (Vector)
dymeclin
Gene Symbol
DYM
HGNC ID
HGNC:21317
ORF Size (aa)
2010
ORF Size (bp)
2010 bp
RefSeq ID
NM_017653
RefSeq Synonyms
NM_017653, BC064394,
Species
human
UniGene ID
Hs.162996
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.