human DUSP9 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DUSP9.
shADV-207445
Ad-h-DUSP9-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DUSP9 (dual specificity phosphatase 9). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MKP-4; MKP4
Description (Vector)
DUSP9 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases, is expressed only in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus.
Gene ID
1852
Gene Name (Vector)
dual specificity phosphatase 9
Gene Symbol
DUSP9
HGNC ID
HGNC:3076
ORF Size (aa)
1155
ORF Size (bp)
1155 bp
RefSeq ID
NM_001395
RefSeq Synonyms
NM_001395, NM_001318503, BC060837,
Species
human
UniGene ID
Hs.144879
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.