human DLST shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DLST.
shADV-207063
Ad-h-DLST-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DLST (dihydrolipoamide S-succinyltransferase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2-oxoglutarate dehydrogenase complex component E2; dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex); Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial; DLTS; E2K; OGDC-E2
Description (eCommerce)
DLST is a mitochondrial protein that belongs to the 2-oxoacid dehydrogenase family. This protein is one of the three components (the E2 component) of the 2-oxoglutarate dehydrogenase complex that catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) [taken from NCBI Entrez Gene (Gene ID: 1743)].
Description (Vector)
DLST encodes a mitochondrial protein that belongs to the 2-oxoacid dehydrogenase family. This protein is one of the three components (the E2 component) of the 2-oxoglutarate dehydrogenase complex that catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). Alternatively spliced transcript variants have been found for this gene.
Gene ID
1743
Gene Name (eCommerce)
dihydrolipoamide S-succinyltransferase
Gene Name (Vector)
dihydrolipoamide S-succinyltransferase
Gene Symbol
DLST
HGNC ID
HGNC:2911
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1362
ORF Size (bp)
1362 bp
Protein Name (eCommerce)
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
RefSeq ID
NM_001933
RefSeq Synonyms
NM_001933, NM_001244883, BC001922, BC000302,
Research Areas
Acyltransferase,Metabolism/Metabolic Process,Mitochondrion
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
DLST is a mitochondrial protein that belongs to the 2-oxoacid dehydrogenase family. This protein is one of the three components (the E2 component) of the 2-oxoglutarate dehydrogenase complex that catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) [taken from NCBI Entrez Gene (Gene ID: 1743)].
UniGene ID
Hs.525459
UniProt ID (eCommerce)
P36957
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.