human DLC1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DLC1.
shADV-207033
Ad-h-DLC1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DLC1 (DLC1 Rho GTPase activating protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ARHGAP7; HP; p122-RhoGAP; STARD12
Description (Vector)
DLC1 encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. DLC1 functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.
Gene ID
10395
Gene Name (Vector)
DLC1 Rho GTPase activating protein
Gene Symbol
DLC1
HGNC ID
HGNC:2897
ORF Size (aa)
4587
ORF Size (bp)
4587 bp
RefSeq ID
NM_006094
RefSeq Synonyms
NM_182643, NM_024767, NM_006094, NM_001316668, NM_001164271, BC054511, BC049842,
Species
human
UniGene ID
Hs.134296
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.