human DES shRNA silencing Adenovirus

Name 
Ad-h-DES-shRNA
Cat No 
shADV-206889
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human DES.

shADV-206889
Ad-h-DES-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DES (desmin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CSM1; CSM2; LGMD2R
Description (Vector)
DES encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
Gene ID
1674
Gene Name (Vector)
desmin
Gene Symbol
DES
HGNC ID
HGNC:2770
ORF Size (aa)
1413
ORF Size (bp)
1413 bp
RefSeq ID
NM_001927
RefSeq Synonyms
NM_001927, BC032116,
Species
human
UniGene ID
Hs.594952

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.