human DDX51 shRNA silencing Adenovirus

Name 
Ad-h-DDX51-shRNA
Cat No 
shADV-206767
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human DDX51.

shADV-206767
Ad-h-DDX51-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DDX51 (DEAD-box helicase 51). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ATP-dependent RNA helicase DDX51; DEAD (Asp-Glu-Ala-Asp) box polypeptide 51; DEAD box protein 51
Description (eCommerce)
DDX51 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX51 may function in biogenesis of the 60S ribosomal subunit.
Gene ID
317781
Gene Name (eCommerce)
DEAD-box helicase 51
Gene Name (Vector)
DEAD-box helicase 51
Gene Symbol
DDX51
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2001
ORF Size (bp)
2001 bp
Protein Name (eCommerce)
ATP-dependent RNA helicase DDX51
RefSeq ID
NM_175066
RefSeq Synonyms
NM_175066, BC040185,
Research Areas
Helicase Activity,RNA Binding,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
DDX51 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX51 may function in biogenesis of the 60S ribosomal subunit.
UniGene ID
Hs.445168
UniProt ID (eCommerce)
Q8N8A6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.