human DDX3Y shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DDX3Y.
shADV-206757
Ad-h-DDX3Y-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DDX3Y (DEAD-box helicase 3, Y-linked). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DBY
Description (Vector)
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it has a homolog on the X chromosome. The gene mutation causes male infertility, Sertoli cell-only syndrome or severe hypospermatogenesis, suggesting that this gene plays a key role in the spermatogenic process. Alternatively spliced variants, encoding the same protein, have been identified.
Gene ID
8653
Gene Name (Vector)
DEAD-box helicase 3, Y-linked
Gene Symbol
DDX3Y
HGNC ID
HGNC:2699
ORF Size (aa)
1983
ORF Size (bp)
1983 bp
RefSeq ID
NM_004660
RefSeq Synonyms
NM_004660, NM_001324195, NM_001302552, NM_001122665, BC034942,
Species
human
UniGene ID
Hs.99120
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.