human DDX24 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DDX24.
shADV-206744
Ad-h-DDX24-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DDX24 (DEAD-box helicase 24). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ATP-dependent RNA helicase DDX24; DEAD (Asp-Glu-Ala-Asp) box helicase 24; DEAD (Asp-Glu-Ala-Asp) box polypeptide 24; DEAD box protein 24; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 24; S. cerevisiae CHL1-like helicase
Description (eCommerce)
DDX24 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. The specific function of DDX24 has not been elucidated.
Description (Vector)
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which shows little similarity to any of the other known human DEAD box proteins, but shows a high similarity to mouse Ddx24 at the amino acid level.
Gene ID
57062
Gene Name (eCommerce)
DEAD-box helicase 24
Gene Name (Vector)
DEAD-box helicase 24
Gene Symbol
DDX24
HGNC ID
HGNC:13266
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2415
ORF Size (bp)
2415 bp
Protein Name (eCommerce)
ATP-dependent RNA helicase DDX24
RefSeq ID
NM_020414
RefSeq Synonyms
NM_020414, BC096826, BC009406, BC008847,
Research Areas
Helicase Activity,RNA Binding,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
DDX24 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. The specific function of DDX24 has not been elucidated.
UniGene ID
Hs.510328
UniProt ID (eCommerce)
Q9GZR7
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.