human DDAH1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DDAH1.
shADV-206691
Ad-h-DDAH1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DDAH1 (dimethylarginine dimethylaminohydrolase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DDAH; DDAH-1; DDAHI; dimethylargininase-1; Dimethylarginine dimethylaminohydrolase 1; epididymis secretory protein Li 16; HEL-S-16; N(G),N(G)-dimethylarginine dimethylaminohydrolase 1; NG, NG-dimethylarginine dimethylaminohydrolase
Description (eCommerce)
Dimethylargininase-1 (DDAH1) hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Therefore, DDAH1 has a role in the regulation of nitric oxide generation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O94760].
Description (Vector)
DDAH1 belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity.
Gene ID
23576
Gene Name (eCommerce)
dimethylarginine dimethylaminohydrolase 1
Gene Name (Vector)
dimethylarginine dimethylaminohydrolase 1
Gene Symbol
DDAH1
HGNC ID
HGNC:2715
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
858
ORF Size (bp)
858 bp
Protein Name (eCommerce)
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
RefSeq ID
NM_012137
RefSeq Synonyms
NM_012137, NM_001330655, NM_001134445, BC033680,
Research Areas
Angiogenesis,Cardiovascular,Mitochondrion
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,developmental_biology
Species
human
Target Sentence
Dimethylargininase-1 (DDAH1) hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Therefore, DDAH1 has a role in the regulation of nitric oxide generation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O94760].
UniGene ID
Hs.379858
UniProt ID (eCommerce)
O94760
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.