human DCTD shRNA silencing Adenovirus

Name 
Ad-h-DCTD-shRNA
Cat No 
shADV-206671
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human DCTD.

shADV-206671
Ad-h-DCTD-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DCTD (dCMP deaminase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
DCTD catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
1635
Gene Name (Vector)
dCMP deaminase
Gene Symbol
DCTD
HGNC ID
HGNC:2710
ORF Size (aa)
537
ORF Size (bp)
537 bp
RefSeq ID
NM_001921
RefSeq Synonyms
NM_001921, NM_001012732, BC088357, BC001286,
Species
human
UniGene ID
Hs.183850

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.