human DARC shRNA silencing Adenovirus

Name 
Ad-h-DARC-shRNA
Cat No 
shADV-206602
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human ACKR1.

shADV-206602
Ad-h-DARC-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ACKR1 (atypical chemokine receptor 1 (Duffy blood group)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CCBP1; CD234; DARC; Dfy; FY; GPD; GpFy; WBCQ1
Description (Vector)
DARC is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
2532
Gene Name (Vector)
atypical chemokine receptor 1 (Duffy blood group)
Gene Symbol
ACKR1
HGNC ID
HGNC:4035
ORF Size (aa)
1011
ORF Size (bp)
1011 bp
RefSeq ID
NM_002036
RefSeq Synonyms
NM_002036, NM_001122951, BC017817,
Species
human
UniGene ID
Hs.153381

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.