human DARC shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

ACKR1

Gene Name

atypical chemokine receptor 1 (Duffy blood group)

Gene ID

2532

Gene Synonyms

CCBP1; CD234; DARC; Dfy; FY; GPD; GpFy; WBCQ1

ORF Size

1011 bp

RefSeq#

NM_002036

Gene Description

DARC is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.153381

HGNC ID

HGNC:4035