human DAPK3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DAPK3.
shADV-206596
Ad-h-DAPK3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DAPK3 (death associated protein kinase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DAP kinase 3; DAP-like kinase; death-associated protein kinase 3; DLK; MYPT1 kinase; ZIP; ZIPK; ZIP-kinase; zipper-interacting protein kinase
Description (eCommerce)
Zipper-interacting protein kinase (ZIPK) is a serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation, actin cytoskeleton reorganization, cell motility, smooth muscle contraction, and mitosis, particularly cytokinesis. ZIPK regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O43293].
Description (Vector)
Death-associated protein kinase 3 (DAPK3) induces morphological changes in apoptosis when overexpressed in mammalian cells. These results suggest that DAPK3 may play a role in the induction of apoptosis.
Gene ID
1613
Gene Name (eCommerce)
death associated protein kinase 3
Gene Name (Vector)
death associated protein kinase 3
Gene Symbol
DAPK3
HGNC ID
HGNC:2676
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1365
ORF Size (bp)
1365 bp
Protein Name (eCommerce)
Death-associated protein kinase 3
RefSeq ID
NM_001348
RefSeq Synonyms
NM_001348, BC126432, BC126430,
Research Areas
Apoptosis,Autophagy,Bladder Cancer,Cancer,Cell Cycle,Chromatin Remodeling,Cytoskeleton,Kinase/Phosphatase,Neurobiology,Neurodevelopment,Signal Transduction,Transcription Factor/Regulator,Translational Control,Wnt Signaling
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,developmental_biology,genetics,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
Zipper-interacting protein kinase (ZIPK) is a serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation, actin cytoskeleton reorganization, cell motility, smooth muscle contraction, and mitosis, particularly cytokinesis. ZIPK regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O43293].
UniGene ID
Hs.631844
UniProt ID (eCommerce)
O43293
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.