human CYP7A1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CYP7A1.
shADV-206529
Ad-h-CYP7A1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CYP7A1 (cytochrome P450 family 7 subfamily A member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CP7A; CYP7; CYPVII
Description (Vector)
CYP7A1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis.
Gene ID
1581
Gene Name (Vector)
cytochrome P450 family 7 subfamily A member 1
Gene Symbol
CYP7A1
HGNC ID
HGNC:2651
ORF Size (aa)
1515
ORF Size (bp)
1515 bp
RefSeq ID
NM_000780
RefSeq Synonyms
NM_000780, BC112184, BC101777,
Species
human
UniGene ID
Hs.1644
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.