human CYB5A shRNA silencing Adenovirus

Name 
Ad-h-CYB5A-shRNA
Cat No 
shADV-206393
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human CYB5A.

shADV-206393
Ad-h-CYB5A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CYB5A (cytochrome b5 type A). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CYB5; MCB5
Description (Vector)
CYB5A is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene.
Gene ID
1528
Gene Name (Vector)
cytochrome b5 type A
Gene Symbol
CYB5A
HGNC ID
HGNC:2570
ORF Size (aa)
405
RefSeq ID
NM_001914
RefSeq Synonyms
NM_148923, NM_001914, NM_001190807, BC015182,
Species
human
UniGene ID
Hs.465413

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.