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human CTNND2 shRNA silencing Adenovirus

Name 
Ad-h-CTNND2-shRNA
Cat No 
shADV-206253
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human CTNND2.

shADV-206253
Ad-h-CTNND2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CTNND2 (catenin delta 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GT24; NPRAP
Description (Vector)
CTNND2 encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. CTNND2 is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. CTNND2 resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome.
Gene ID
1501
Gene Name (Vector)
catenin delta 2
Gene Symbol
CTNND2
HGNC ID
HGNC:2516
ORF Size (aa)
3675
ORF Size (bp)
3675 bp
RefSeq ID
NM_001332
RefSeq Synonyms
NM_001332, NM_001288717, NM_001288716, NM_001288715, BC111837,
Species
human
UniGene ID
Hs.314543

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.