Promotional banner reading 'FALL SAVINGS' with expiry date August 31 on an orange background; features a group of people with orange stacked blocks on the right and discounts for services and catalog products.

human CTNND2 shRNA silencing AAV

Name 
AAV-h-CTNND2-shRNA
Cat No 
shAAV-206253
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CTNND2.

shAAV-206253
AAV-h-CTNND2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CTNND2 (catenin delta 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GT24; NPRAP
Description (Vector)
CTNND2 encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. CTNND2 is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. CTNND2 resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome.
Gene ID
1501
Gene Name (Vector)
catenin delta 2
Gene Symbol
CTNND2
HGNC ID
HGNC:2516
ORF Size (aa)
3675
ORF Size (bp)
3675 bp
RefSeq ID
NM_001332
RefSeq Synonyms
NM_001332, NM_001288717, NM_001288716, NM_001288715, BC111837,
Species
human
UniGene ID
Hs.314543

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.