human CTNND1 shRNA silencing Adenovirus

Name 
Ad-h-CTNND1-shRNA
Cat No 
shADV-206252
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CTNND1.

shADV-206252
Ad-h-CTNND1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CTNND1 (catenin delta 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BCDS2; cadherin-associated Src substrate; CAS; catenin (cadherin-associated protein), delta 1; catenin delta-1; CTNND; p120; p120 catenin; p120(CAS); p120(CTN); P120CAS; P120CTN
Description (eCommerce)
CTNND1 is an Armadillo repeat domain protein and member of the p120 protein family. The major function of CTNND1 involves the regulation of cadherins to influence cell-cell interactions. CTNND1 regulates cadherins by controlling cadherin turnover and/or trafficking. CTNND1 has also been found to play a role in the regulation of the actin cytoskeleton by modulating the activity of small GTPase Rho family members. CTNND1 is a substrate of the nonreceptor tyrosine kinase src and may play a role in the regulation of factors that regulate transcription.
Description (Vector)
CTNND1 encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene.
Gene ID
1500
Gene Name (eCommerce)
catenin delta 1
Gene Name (Vector)
catenin delta 1
Gene Symbol
CTNND1
HGNC ID
HGNC:2515
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2802
ORF Size (bp)
2802 bp
Protein Name (eCommerce)
Catenin delta-1
RefSeq ID
NM_001331
RefSeq Synonyms
NM_001331, NM_001206891, NM_001206890, NM_001206889, NM_001206888, NM_001206887, NM_001206886, NM_001206885, NM_001206884, NM_001206883, NM_001085469, NM_001085468, NM_001085467, NM_001085466, NM_001085465, NM_001085464, NM_001085463, NM_001085462, NM_001085461, NM_001085460, NM_001085459, NM_001085458, BC075795, BC010501,
Research Areas
Cytoskeleton,EGFR Signaling,FGF Signaling,Immunology,Signal Transduction,Transcription Factor/Regulator,Translational Control,Wnt Signaling
Research Areas (Faceted)
cell_biology,immunology,signal_transduction,transcription_translation
Species
human
Target Sentence
CTNND1 is an Armadillo repeat domain protein and member of the p120 protein family. The major function of CTNND1 involves the regulation of cadherins to influence cell-cell interactions. CTNND1 regulates cadherins by controlling cadherin turnover and/or trafficking. CTNND1 has also been found to play a role in the regulation of the actin cytoskeleton by modulating the activity of small GTPase Rho family members. CTNND1 is a substrate of the nonreceptor tyrosine kinase src and may play a role in the regulation of factors that regulate transcription.
UniGene ID
Hs.166011
UniProt ID (eCommerce)
O60716

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.