human CNGB1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CNGB1.
shADV-205577
Ad-h-CNGB1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CNGB1 (cyclic nucleotide gated channel beta 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CNCG2; CNCG3L; CNCG4; CNG4; CNGB1B; GAR1; GARP; GARP2; RCNC2; RCNCb; RCNCbeta; RP45
Description (Vector)
In humans, the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP. This channel consists of two subunits, alpha and beta, with the protein encoded by this gene representing the beta subunit. Defects in this gene are a cause of cause of retinitis pigmentosa type 45. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
1258
Gene Name (Vector)
cyclic nucleotide gated channel beta 1
Gene Symbol
CNGB1
HGNC ID
HGNC:2151
ORF Size (aa)
3753
ORF Size (bp)
3753 bp
RefSeq ID
NM_001297
RefSeq Synonyms
NM_001297, NM_001286130, NM_001135639, BC156722, BC140364,
Species
human
UniGene ID
Hs.147062
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.