human CLDN19 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CLDN19.
shADV-205376
Ad-h-CLDN19-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CLDN19 (claudin 19). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HOMG5
Description (Vector)
The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Gene ID
149461
Gene Name (Vector)
claudin 19
Gene Symbol
CLDN19
HGNC ID
HGNC:2040
ORF Size (aa)
636
RefSeq ID
NM_148960
RefSeq Synonyms
NM_148960, NM_001185117, NM_001123395, BC030524,
Species
human
UniGene ID
Hs.496270
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.