human CHRNA3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CHRNA3.
shADV-205209
Ad-h-CHRNA3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
LNCR2; NACHRA3; PAOD2
Description (Vector)
This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.
Gene ID
1136
Gene Name (Vector)
cholinergic receptor nicotinic alpha 3 subunit
Gene Symbol
CHRNA3
HGNC ID
HGNC:1957
ORF Size (aa)
1515
ORF Size (bp)
1515 bp
RefSeq ID
NM_000743
RefSeq Synonyms
NM_001166694, NM_000743, BC098443, BC006114, BC002996, BC001642, BC000513,
Species
human
UniGene ID
Hs.89605
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.