human CHMP5 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CHMP5.
shADV-205168
Ad-h-CHMP5-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CHMP5 (charged multivesicular body protein 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C9orf83; CGI-34; HSPC177; PNAS-2; SNF7DC2; Vps60
Description (Vector)
CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 (PubMed 16730941)).(supplied by OMIM, Mar 2008)
Gene ID
51510
Gene Name (Vector)
charged multivesicular body protein 5
Gene Symbol
CHMP5
HGNC ID
HGNC:26942
ORF Size (aa)
660
ORF Size (bp)
660 bp
RefSeq ID
NM_016410
RefSeq Synonyms
NM_016410, NM_001195536, BC021168, BC020796, BC016698, BC007457, BC006974,
Species
human
UniGene ID
Hs.635313
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.