human CERKL shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CERKL.
shADV-205017
Ad-h-CERKL-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CERKL (ceramide kinase like). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RP26
Description (Vector)
CERKL was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. CERKL encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.
Gene ID
375298
Gene Name (Vector)
ceramide kinase like
Gene Symbol
CERKL
HGNC ID
HGNC:21699
ORF Size (aa)
1599
ORF Size (bp)
1599 bp
RefSeq ID
NM_201548
RefSeq Synonyms
NM_201548, NM_001160277, NM_001030313, NM_001030312, NM_001030311, BC137499, BC137498,
Species
human
UniGene ID
Hs.715753
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.