human CDH4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CDH4.
shADV-204825
Ad-h-CDH4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CDH4 (cadherin 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CAD4; R-CAD; RCAD
Description (Vector)
CDH4 is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.
Gene ID
1002
Gene Name (Vector)
cadherin 4
Gene Symbol
CDH4
HGNC ID
HGNC:1763
ORF Size (aa)
2751
ORF Size (bp)
2751 bp
RefSeq ID
NM_001794
RefSeq Synonyms
NM_001794, NM_001252339, NM_001252338, BC112150, BC101651,
Species
human
UniGene ID
Hs.598638
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.