human CDH3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CDH3.
shADV-204824
Ad-h-CDH3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CDH3 (cadherin 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CDHP; HJMD; PCAD
Description (Vector)
CDH3 is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. CDH3 is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
Gene ID
1001
Gene Name (Vector)
cadherin 3
Gene Symbol
CDH3
HGNC ID
HGNC:1762
ORF Size (aa)
2490
ORF Size (bp)
2490 bp
RefSeq ID
NM_001793
RefSeq Synonyms
NM_001793, NM_001317196, NM_001317195, BC041846, BC014462,
Species
human
UniGene ID
Hs.191842
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.