human CD82 shRNA silencing Adenovirus

Name
Ad-h-CD82-shRNA

Cat No
shADV-204689

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human CD82.

shADV-204689

Ad-h-CD82-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CD82 (CD82 molecule). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

4F9; C33; GR15; IA4; KAI1; R2; SAR2; ST6; TSPAN27

Description (Vector)

This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene ID

3732

Gene Name (Vector)

CD82 molecule

Gene Symbol

CD82

HGNC ID

HGNC:6210

ORF Size (aa)

804

RefSeq ID

NM_002231

RefSeq Synonyms

NM_002231, NM_001024844, BC001821, BC000726,

Species

human

UniGene ID

Hs.527778

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.