human CD79B shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CD79B.
shADV-204684
Ad-h-CD79B-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CD79B (CD79b molecule). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AGM6; B29; B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; CD antigen CD79b; CD79b antigen (immunoglobulin-associated beta); CD79b molecule, immunoglobulin-associated beta; IGB; Ig-beta; immunoglobulin-associated B29 protein
Description (eCommerce)
CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P40259].
Description (Vector)
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene ID
974
Gene Name (eCommerce)
CD79b molecule
Gene Name (Vector)
CD79b molecule
Gene Symbol
CD79B
HGNC ID
HGNC:1699
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
690
Protein Name (eCommerce)
B-cell antigen receptor complex-associated protein beta chain
RefSeq ID
NM_000626
RefSeq Synonyms
NM_021602, NM_001329050, NM_001039933, NM_000626, BC032651, BC030210, BC002975,
Research Areas
B-cell Receptor Signaling,Golgi Apparatus,Immunology,Signal Transduction
Research Areas (Faceted)
signal_transduction,immunology,cell_biology
Species
human
Target Sentence
CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P40259].
UniGene ID
Hs.89575
UniProt ID (eCommerce)
P40259
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.