human CD55 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CD55.
shADV-204666
Ad-h-CD55-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CD55 (CD55 molecule (Cromer blood group)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CR; CROM; DAF; TC
Description (Vector)
CD55 encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Gene ID
1604
Gene Name (Vector)
CD55 molecule (Cromer blood group)
Gene Symbol
CD55
HGNC ID
HGNC:2665
ORF Size (aa)
1146
ORF Size (bp)
1146 bp
RefSeq ID
NM_000574
RefSeq Synonyms
NM_001300904, NM_001300903, NM_001300902, NM_001114752, NM_000574, BC001288,
Species
human
UniGene ID
Hs.126517
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.