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human CD3EAP shRNA silencing Adenovirus

Name 
Ad-h-CD3EAP-shRNA
Cat No 
shADV-204649
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human CD3EAP.

shADV-204649
Ad-h-CD3EAP-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CD3EAP (CD3e molecule associated protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
A34.5; antisense to ERCC-1 protein; ASE1; ASE-1; CAST; CD3e antigen, epsilon polypeptide associated protein; CD3e molecule, epsilon associated protein; CD3E-associated protein; CD3-epsilon-associated protein; DNA-directed RNA polymerase I subunit RPA34; PAF49; RNA polymerase I-associated factor PAF49
Description (eCommerce)
PAF49 is subunit of RNA polymerase I. PAF49/CAST has been shown to interact with activator upstream binding factor (UBF) and plays an important role in rDNA transcription.
Gene ID
10849
Gene Name (eCommerce)
CD3e molecule associated protein
Gene Name (Vector)
CD3e molecule associated protein
Gene Symbol
CD3EAP
HGNC ID
HGNC:24219
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1533
ORF Size (bp)
1533 bp
Protein Name (eCommerce)
DNA-directed RNA polymerase I subunit RPA34
RefSeq ID
NM_012099
RefSeq Synonyms
NM_012099, NM_001297590, BC108889, BC038992,
Research Areas
Epigenetic Regulation of Gene Expression,Mitochondrion,Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,genetics,signal_transduction,transcription_translation
Species
human
Target Sentence
PAF49 is subunit of RNA polymerase I. PAF49/CAST has been shown to interact with activator upstream binding factor (UBF) and plays an important role in rDNA transcription.
UniGene ID
Hs.710495
UniProt ID (eCommerce)
O15446

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.