human CD151 shRNA silencing Adenovirus

Name 
Ad-h-CD151-shRNA
Cat No 
shADV-204577
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human CD151.

shADV-204577
Ad-h-CD151-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CD151 (CD151 molecule (Raph blood group)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GP27; MER2; PETA-3; RAPH; SFA1; TSPAN24
Description (Vector)
CD151 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.
Gene ID
977
Gene Name (Vector)
CD151 molecule (Raph blood group)
Gene Symbol
CD151
HGNC ID
HGNC:1630
ORF Size (aa)
762
ORF Size (bp)
762 bp
RefSeq ID
NM_004357
RefSeq Synonyms
NM_139030, NM_139029, NM_004357, NM_001039490, BC013302, BC001374,
Species
human
UniGene ID
Hs.654379

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.