human CD151 shRNA silencing Adenovirus

Name
Ad-h-CD151-shRNA

Cat No
shADV-204577

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human CD151.

shADV-204577

Ad-h-CD151-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CD151 (CD151 molecule (Raph blood group)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

GP27; MER2; PETA-3; RAPH; SFA1; TSPAN24

Description (Vector)

CD151 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.

Gene ID

977

Gene Name (Vector)

CD151 molecule (Raph blood group)

Gene Symbol

CD151

HGNC ID

HGNC:1630

ORF Size (aa)

762

ORF Size (bp)

762 bp

RefSeq ID

NM_004357

RefSeq Synonyms

NM_139030, NM_139029, NM_004357, NM_001039490, BC013302, BC001374,

Species

human

UniGene ID

Hs.654379

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.