human CCR8 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CCR8.
shADV-204548
Ad-h-CCR8-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CCR8 (C-C motif chemokine receptor 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CC-CKR-8; CCR-8; CDw198; CKRL1; CMKBR8; CMKBRL2; CY6; GPRCY6; TER1
Description (Vector)
CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. CCR8 is located at the chemokine receptor gene cluster region.
Gene ID
1237
Gene Name (Vector)
C-C motif chemokine receptor 8
Gene Symbol
CCR8
HGNC ID
HGNC:1609
ORF Size (aa)
819
ORF Size (bp)
819 bp
RefSeq ID
NM_005201
RefSeq Synonyms
NM_005201, BC107159, BC107152, BC074743, BC069067,
Species
human
UniGene ID
Hs.716265
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.