human CCNDBP1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CCNDBP1.
shADV-204494
Ad-h-CCNDBP1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CCNDBP1 (cyclin D1 binding protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DIP1; GCIP; HHM
Description (Vector)
CCNDBP1 was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene.
Gene ID
23582
Gene Name (Vector)
cyclin D1 binding protein 1
Gene Symbol
CCNDBP1
HGNC ID
HGNC:1587
ORF Size (aa)
1083
ORF Size (bp)
1083 bp
RefSeq ID
NM_012142
RefSeq Synonyms
NM_037370, NM_012142, BC009689,
Species
human
UniGene ID
Hs.688009
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.