human CCNB3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CCNB3.
shADV-204482
Ad-h-CCNB3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CCNB3 (cyclin B3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
CCNB3 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as positive regulators of cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle. Different cyclins exhibit distinct expression and degradation patterns, which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chicken and drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and may be required for proper spindle reorganization and restoration of the interphase nucleus. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID
85417
Gene Name (Vector)
cyclin B3
Gene Symbol
CCNB3
HGNC ID
HGNC:18709
ORF Size (aa)
4185
ORF Size (bp)
4185 bp
RefSeq ID
NM_033670
RefSeq Synonyms
NM_033670, NM_033031, BC172544, BC172237,
Species
human
UniGene ID
Hs.130310
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.