human CCL2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CCL2.
shADV-204430
Ad-h-CCL2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CCL2 (C-C motif chemokine ligand 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF
Description (Vector)
CCL2 is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
Gene ID
6347
Gene Name (Vector)
C-C motif chemokine ligand 2
Gene Symbol
CCL2
HGNC ID
HGNC:10618
ORF Size (aa)
300
RefSeq ID
NM_002982
RefSeq Synonyms
NM_002982, BC009716,
Species
human
UniGene ID
Hs.303649
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.