human CBX8 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CBX8.
shADV-204204
Ad-h-CBX8-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CBX8 (chromobox 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
chromobox homolog 8 (Pc class homolog, Drosophila); chromobox protein homolog 8; hPc3; Pc class 3 homolog; PC3; polycomb 3; Polycomb 3 homolog; RC1; rectachrome 1
Description (eCommerce)
CBX8 is part of the polycomb group of proteins that are important in embryogenesis and human tumorigenesis and regulates a number of genes involved in cell growth and survival. There are at least 5 CBX proteins in mammals. CBX proteins associate with the core polycomb repressive complex 1 (PRC1) that functions to maintain the transcriptionally repressive state of genes during development.
Gene ID
57332
Gene Name (eCommerce)
chromobox 8
Gene Name (Vector)
chromobox 8
Gene Symbol
CBX8
HGNC ID
HGNC:15962
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1170
ORF Size (bp)
1170 bp
Protein Name (eCommerce)
Chromobox protein homolog 8
RefSeq ID
NM_020649
RefSeq Synonyms
NM_020649, BC019289, BC009376, BC008937,
Research Areas
Chromatin Remodeling,Complexome,Histone Modification,Polycomb Proteins,RNA Binding,Transcription Factor/Regulator,Ubiquitination
Research Areas (Faceted)
transcription_translation,cell_biology,genetics
Species
human
Target Sentence
CBX8 is part of the polycomb group of proteins that are important in embryogenesis and human tumorigenesis and regulates a number of genes involved in cell growth and survival. There are at least 5 CBX proteins in mammals. CBX proteins associate with the core polycomb repressive complex 1 (PRC1) that functions to maintain the transcriptionally repressive state of genes during development.
UniGene ID
Hs.387258
UniProt ID (eCommerce)
Q9HC52
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.