human CASP6 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CASP6.
shADV-204120
Ad-h-CASP6-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CASP6 (caspase 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MCH2
Description (Vector)
CASP6 encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.
Gene ID
839
Gene Name (Vector)
caspase 6
Gene Symbol
CASP6
HGNC ID
HGNC:1507
ORF Size (aa)
882
ORF Size (bp)
882 bp
RefSeq ID
NM_001226
RefSeq Synonyms
NM_032992, NM_001226, BC004460, BC000305,
Species
human
UniGene ID
Hs.654616
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.