human CAMK2A shRNA silencing Adenovirus

Name 
Ad-h-CAMK2A-shRNA
Cat No 
shADV-203996
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CAMK2A.

shADV-203996
Ad-h-CAMK2A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CAMK2A (calcium/calmodulin dependent protein kinase II alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CAMKA
Description (Vector)
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
Gene ID
815
Gene Name (Vector)
calcium/calmodulin dependent protein kinase II alpha
Gene Symbol
CAMK2A
HGNC ID
HGNC:1460
ORF Size (aa)
1437
ORF Size (bp)
1437 bp
RefSeq ID
NM_171825
RefSeq Synonyms
NM_171825, NM_015981, BC040457,
Species
human
UniGene ID
Hs.716391

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.