human C4BPA shRNA silencing Adenovirus

Name 
Ad-h-C4BPA-shRNA
Cat No 
shADV-203440
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human C4BPA.

shADV-203440
Ad-h-C4BPA-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human C4BPA (complement component 4 binding protein alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C4BP; PRP
Description (Vector)
C4BPA encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster.
Gene ID
722
Gene Name (Vector)
complement component 4 binding protein alpha
Gene Symbol
C4BPA
HGNC ID
HGNC:1325
ORF Size (aa)
1794
ORF Size (bp)
1794 bp
RefSeq ID
NM_000715
RefSeq Synonyms
NM_000715, BC022312,
Species
human
UniGene ID
Hs.1012

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.