Promotional banner reading 'FALL SAVINGS' with expiry date August 31 on an orange background; features a group of people with orange stacked blocks on the right and discounts for services and catalog products.

human BRD2 shRNA silencing Adenovirus

Name 
Ad-h-BRD2-shRNA
Cat No 
shADV-202256
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human BRD2.

shADV-202256
Ad-h-BRD2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human BRD2 (bromodomain containing 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BRD2 intronic transcript 1; BRD2-IT1; bromodomain-containing protein 2; D6S113E; female sterile homeotic-related gene 1; FSH; FSRG1; NAT; O27.1.1; really interesting new gene 3 protein; RING3; RNF3
Description (eCommerce)
BRD2 (bromodomain-containing 2) is a nuclear mitogen-activated kinase that plays a role in transcription of cell-cycle-regulated genes by functioning as an adapter protein that recruits E2F and chromatin remodeling factors to E2F response elements.
Description (Vector)
BRD2 encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. BRD2 has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene.
Gene ID
6046
Gene Name (eCommerce)
bromodomain containing 2
Gene Name (Vector)
bromodomain containing 2
Gene Symbol
BRD2
HGNC ID
HGNC:1103
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2511
ORF Size (bp)
2511 bp
Protein Name (eCommerce)
Bromodomain-containing protein 2
RefSeq ID
NM_005104
RefSeq Synonyms
NM_005104, NM_001291986, NM_001199456, NM_001199455, NM_001113182, BC063840,
Research Areas
Chromatin Remodeling,Kinase/Phosphatase,Spermatogenesis,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,developmental_biology,genetics,signal_transduction,transcription_translation
Species
human
Target Sentence
BRD2 (bromodomain-containing 2) is a nuclear mitogen-activated kinase that plays a role in transcription of cell-cycle-regulated genes by functioning as an adapter protein that recruits E2F and chromatin remodeling factors to E2F response elements.
UniGene ID
Hs.75243
UniProt ID (eCommerce)
P25440

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.