human BRD2 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-202256
Availability:
4-5 weeks
Name:
AAV-h-BRD2-shRNA
This is an AAV expressing shRNA for silencing of Human BRD2.
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Product Info
- Knockdown
- >80% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- BRD2
- Gene Name
- bromodomain containing 2
- Gene ID
- 6046
- Gene Synonyms
- D6S113E; FSH; FSRG1; NAT; O27.1.1; RING3; RNF3
- ORF Size
- 2511 bp
- RefSeq#
- NM_005104
- Gene Description
- BRD2 encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. BRD2 has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene.
- UniGene ID
- Hs.75243
- HGNC ID
- HGNC:1103
Related Products
Product | Cat No. |
---|---|
AAV-h-BRD2 | AAV-202256 |
AAV-m-BRD2 | AAV-254073 |
Ad-h-BRD2 | ADV-202256 |
Ad-m-BRD2 | ADV-254073 |
AAV-m-BRD2-shRNA | shAAV-254073 |
Ad-h-BRD2-shRNA | shADV-202256 |
Ad-m-BRD2-shRNA | shADV-254073 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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