human BOP1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human BOP1.
shADV-202234
Ad-h-BOP1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human BOP1 (block of proliferation 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Block of proliferation 1 protein; ribosome biogenesis protein BOP1
Description (eCommerce)
BOP1 (block of proliferation 1) is a component of the PeBoW (Pes1, Bop, WDR12) complex that plays a role in the processing of 28S and 5.8S ribosomal RNAs and the formation of the 60S ribosome. BOP1 contains seven WD repeats and was originally identified as a cDNA which inhibited cell proliferation. The deregulation of the BOP1 gene is proposed to contribute to colorectal tumorigenesis.
Gene ID
23246
Gene Name (eCommerce)
block of proliferation 1
Gene Name (Vector)
block of proliferation 1
Gene Symbol
BOP1
HGNC ID
HGNC:15519
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2241
ORF Size (bp)
2241 bp
Protein Name (eCommerce)
Ribosome biogenesis protein BOP1
RefSeq ID
NM_015201
RefSeq Synonyms
NM_015201, BC017674, BC013980, BC013787,
Research Areas
Cell Cycle,RNA Processing
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
BOP1 (block of proliferation 1) is a component of the PeBoW (Pes1, Bop, WDR12) complex that plays a role in the processing of 28S and 5.8S ribosomal RNAs and the formation of the 60S ribosome. BOP1 contains seven WD repeats and was originally identified as a cDNA which inhibited cell proliferation. The deregulation of the BOP1 gene is proposed to contribute to colorectal tumorigenesis.
UniGene ID
Hs.645279
UniProt ID (eCommerce)
Q14137
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.