human BICD1 shRNA silencing Adenovirus

Name
Ad-h-BICD1-shRNA

Cat No
shADV-202135

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human BICD1.

shADV-202135

Ad-h-BICD1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human BICD1 (BICD cargo adaptor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

60

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

bicaudal D homolog 1; BICD; bic-D 1; cytoskeleton-like bicaudal D protein homolog 1; protein bicaudal D homolog 1

Description (eCommerce)

Bicaudal D homolog 1(BICD1) regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96G01].

Description (Vector)

BICD1 is one of two human homologs of Drosophila bicaudal-D. It has been implicated in COPI-independent membrane transport from the Golgi apparatus to the endoplasmic reticulum. Two alternative splice variants have been described. Other alternative splice variants that encode different protein isoforms have been described but their full-length nature has not been determined.

Gene ID

636

Gene Name (eCommerce)

BICD cargo adaptor 1

Gene Name (Vector)

BICD cargo adaptor 1

Gene Symbol

BICD1

HGNC ID

HGNC:1049

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2484

ORF Size (bp)

2484 bp

Protein Name (eCommerce)

Protein bicaudal D homolog 1

RefSeq ID

NM_001714

RefSeq Synonyms

NM_001714, NM_001003398, BC136372,

Research Areas

Cytoskeleton,Golgi Apparatus,Host-Virus Interactions,RNA Processing,Transport

Research Areas (Faceted)

infectious_disease,genetics,transcription_translation,cell_biology

Species

human

Target Sentence

Bicaudal D homolog 1(BICD1) regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96G01].

UniGene ID

Hs.505202

UniProt ID (eCommerce)

Q96G01

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.