human BHMT2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human BHMT2.
shADV-202133
Ad-h-BHMT2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human BHMT2 (betaine–homocysteine S-methyltransferase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
23743
Gene Name (Vector)
betaine--homocysteine S-methyltransferase 2
Gene Symbol
BHMT2
HGNC ID
HGNC:1048
ORF Size (aa)
1092
ORF Size (bp)
1092 bp
RefSeq ID
NM_017614
RefSeq Synonyms
NM_017614, NM_001178005, BC020665,
Species
human
UniGene ID
Hs.114172
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.