human BEST3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human BEST3.
shADV-202100
Ad-h-BEST3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human BEST3 (bestrophin 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
VMD2L3
Description (Vector)
BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 (PubMed 12032738); Tsunenari et al., 2003 (PubMed 12907679)).(supplied by OMIM, Mar 2008)
Gene ID
144453
Gene Name (Vector)
bestrophin 3
Gene Symbol
BEST3
HGNC ID
HGNC:17105
ORF Size (aa)
2007
ORF Size (bp)
2007 bp
RefSeq ID
NM_152439
RefSeq Synonyms
NM_152439, NM_032735, NM_001282616, NM_001282615, NM_001282614, NM_001282613, BC166663, BC006440,
Species
human
UniGene ID
Hs.280782
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.