human BBS2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human BBS2.
shADV-201998
Ad-h-BBS2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human BBS2 (Bardet-Biedl syndrome 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BBS; RP74
Description (Vector)
BBS2 is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene forms a multiprotein BBSome complex with six other BBS proteins.
Gene ID
583
Gene Name (Vector)
Bardet-Biedl syndrome 2
Gene Symbol
BBS2
HGNC ID
HGNC:967
ORF Size (aa)
2166
ORF Size (bp)
2166 bp
RefSeq ID
NM_031885
RefSeq Synonyms
NM_031885, BC014140,
Species
human
UniGene ID
Hs.333738
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.