human B4GALT5 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human B4GALT5.
shADV-201912
Ad-h-B4GALT5-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human B4GALT5 (beta-1,4-galactosyltransferase 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
B4Gal-T5; BETA4-GALT-IV; beta4Gal-T5; beta4GalT-V; gt-V
Description (Vector)
B4GALT5 is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The function of the enzyme encoded by this gene is not clear. B4GALT5 was previously designated as B4GALT4 but was renamed to B4GALT5. In the literature it is also referred to as beta4GalT2.
Gene ID
9334
Gene Name (Vector)
beta-1,4-galactosyltransferase 5
Gene Symbol
B4GALT5
HGNC ID
HGNC:928
ORF Size (aa)
1167
ORF Size (bp)
1167 bp
RefSeq ID
NM_004776
RefSeq Synonyms
NM_004776, BC112265, BC104987, BC074873, BC074821,
Species
human
UniGene ID
Hs.370487
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.