human AZIN1 shRNA silencing Adenovirus

Name 
Ad-h-AZIN1-shRNA
Cat No 
shADV-201863
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human AZIN1.

shADV-201863
Ad-h-AZIN1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human AZIN1 (antizyme inhibitor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AZI; AZIA1; OAZI; OAZIN; ODC1L
Description (Vector)
Ornithine decarboxylase (ODC) catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. Ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. The protein encoded by this gene is highly similar to ODC. It binds to ODC antizyme and stabilizes ODC, thus inhibiting antizyme-mediated ODC degradation. Two alternatively spliced transcript variants have been found for this gene.
Gene ID
51582
Gene Name (Vector)
antizyme inhibitor 1
Gene Symbol
AZIN1
HGNC ID
HGNC:16432
ORF Size (aa)
1347
ORF Size (bp)
1347 bp
RefSeq ID
NM_015878
RefSeq Synonyms
NM_148174, NM_015878, NM_001301668, BC019279, BC013420,
Species
human
UniGene ID
Hs.459106

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.