human ATP5E shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ATP5E.
shADV-201716
Ad-h-ATP5E-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ATP5E (ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ATPE; MC5DN3
Description (Vector)
ATP5E encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). ATP5E encodes the epsilon subunit of the catalytic core. Two pseudogenes of this gene are located on chromosomes 4 and 13. Read-through transcripts that include exons from this gene are expressed from the upstream gene SLMO2.
Gene ID
514
Gene Name (Vector)
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
Gene Symbol
ATP5E
HGNC ID
HGNC:838
ORF Size (aa)
156
ORF Size (bp)
156 bp
RefSeq ID
NM_006886
RefSeq Synonyms
NM_006886, NM_001001977, BC105811, BC003671, BC001690,
Species
human
UniGene ID
Hs.177530
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.