human ATP5C1 shRNA silencing Adenovirus

ATP synthase F1 subunit gamma; ATP synthase gamma chain, mitochondrial; ATP synthase subunit gamma, mitochondrial; ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1; ATP5C; ATP5C1; ATP5CL1; F-ATPase gamma subunit; mitochondrial ATP synthase, gamma subunit 1

The gene ATP5C1 encodes the protein ATP synthase subunit gamma, mitochondrial. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. This gene encodes the gamma subunit of the catalytic core [taken from NCBI Entrez Gene (Gene ID: 509)].

ATP5C1 encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). ATP5C1 encodes the gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. ATP5C1 also has a pseudogene on chromosome 14.

509

ATP synthase F1 subunit gamma

ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1

ATP5C1

HGNC:833

9606.0

897

897 bp

ATP synthase subunit gamma, mitochondrial

NM_005174

NM_005174, NM_001320886, NM_001001973, BC020824, BC016812, BC013394, BC000931, BC000470,

Alzheimer's Disease,Cancer,Cardiology,Cell Biology,EGFR Signaling,Huntington's Disease,Metabolism/Metabolic Process,Mitochondrion,Neurobiology,Neurodegeneration,Parkinson's Disease,Signal Transduction,Transport

cancer,signal_transduction,neurobiology,cardiovascular,cell_biology,signal_transduction,neurobiology,metabolism,cell_biology,neurobiology,cell_biology

human

The gene ATP5C1 encodes the protein ATP synthase subunit gamma, mitochondrial. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. This gene encodes the gamma subunit of the catalytic core [taken from NCBI Entrez Gene (Gene ID: 509)].

Hs.271135

P36542