human ARL2BP shRNA silencing Adenovirus

Name 
Ad-h-ARL2BP-shRNA
Cat No 
shADV-201404
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human ARL2BP.

shADV-201404
Ad-h-ARL2BP-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ARL2BP (ADP ribosylation factor like GTPase 2 binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BART; BART1; RP66
Description (Vector)
ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity.
Gene ID
23568
Gene Name (Vector)
ADP ribosylation factor like GTPase 2 binding protein
Gene Symbol
ARL2BP
HGNC ID
HGNC:17146
ORF Size (aa)
459
ORF Size (bp)
459 bp
RefSeq ID
NM_012106
RefSeq Synonyms
NM_012106, BC094878, BC003087,
Species
human
UniGene ID
Hs.645184

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.